Its function is actually antagonistic compared to that of PTH. The fresh new calcitonin receptor is present from the DCT (34, 175), nevertheless molecular device of calcitonin-stimulated calcium supplements reabsorption on the distal nephron is not obvious. It doesn’t involve altered TRPV5 or CaBP-Ddos8K (80).

Moreover it improved PMCA interest in distal tubular muscle (42). Alternatively, the hormone estrogen lack in combination with a minimal-calcium diet CA1b (45). The new determine out-of androgens for the calcium transportation is actually less clear.